Two‐Photon‐Responsive Supramolecular Hydrogel for Controlling Materials Motion in Micrometer Space

Spatiotemporal control of fluidity inside a soft matrix by external stimuli allows real-time manipulation of nano/micromaterials. In this study, we report a two-photon-responsive peptide-based supramolecular hydrogel, the fluidity of which was dramatically controlled with high spatial resolution (10 μm×10 μm×10 μm). The off-on switching of the Brownian motion of nanobeads and chemotaxis of bacteria by two-photon excitation was successfully demonstrated.