Dietary Fiber for the Treatment of Type 2 Diabetes Mellitus: A Meta-Analysis

医学 糖尿病 2型糖尿病 内科学 2型糖尿病 安慰剂 随机对照试验 血红蛋白 内分泌学 病理 替代医学
作者
Robert E. Post,Arch G. Mainous,Dana E. King,Kit N. Simpson
出处
期刊:Journal of the American Board of Family Medicine [American Board of Family Medicine]
卷期号:25 (1): 16-23 被引量:285
标识
DOI:10.3122/jabfm.2012.01.110148
摘要

Background:

The evidence of the relationship between fiber intake and control of diabetes is mixed. The purpose of this study was to determine if an increase in dietary fiber affects glycosylated hemoglobin (HbA1c) and fasting blood glucose in patients with type 2 diabetes mellitus.

Methods:

Randomized studies published from January 1, 1980, to December 31, 2010, that involved an increase in dietary fiber intake as an intervention, evaluated HbA1c and/or fasting blood glucose as an outcome, and used human participants with known type 2 diabetes mellitus were selected for review.

Results:

Fifteen studies met inclusion and exclusion criteria. The overall mean difference of fiber versus placebo was a reduction of fasting blood glucose of 0.85 mmol/L (95% CI, 0.46–1.25). Dietary fiber as an intervention also had an effect on HbA1c over placebo, with an overall mean difference of a decrease in HbA1c of 0.26% (95% CI, 0.02–0.51).

Conclusion:

Overall, an intervention involving fiber supplementation for type 2 diabetes mellitus can reduce fasting blood glucose and HbA1c. This suggests that increasing dietary fiber in the diet of patients with type 2 diabetes is beneficial and should be encouraged as a disease management strategy.
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