化学
苯甲醛
苯胺
药物化学
反应性(心理学)
极性效应
三苯基膦
氰化物
氧化物
有机化学
硫化物
三苯基氧化膦
催化作用
医学
病理
替代医学
作者
Hajime Kuwabara,Yoshihiro Ushigoe,Màsatomo Nojima
出处
期刊:Journal of the Chemical Society
日期:1996-01-01
卷期号: (9): 871-871
被引量:8
摘要
Carbonyl oxides, derived from the ozonolyses of vinyl ethers, readily undergo [3 + 2] cycloadditions with acyl cyanides affording the corresponding cyano-substituted 1,2,4-trioxolanes in isolated yields of 34–88%. In competition experiments, a relative order of reactivity of the carbonyl oxide trapping agents was tentatively deduced; trifluoroacetophenone > α,α-diphenyl-N-methylnitrone (N-methyldiphenyl-methylideneamine N-oxide) > benzoyl cyanide > methyl benzoylformate > α,α,N-triphenylimine [N-(diphenylmethylidene)aniline] benzaldehyde. As expected from the electron-withdrawing ability of the cyano group, 3-cyano-3-phenyl-1,2,4-trioxolane oxidized not only triphenylphosphine but also methyl p-tolyl sulfide and 2,3-dimethylbut-2-ene very easily.
科研通智能强力驱动
Strongly Powered by AbleSci AI