Microgalvanic and Cuprotosis-like-Mediated Dual Engineered Metabolic Interference Strategy to Combat Implant-Associated Infections

experiments validate its potent antibacterial effect in the infected subcutaneous tissue of a rat model. Moreover, the film can facilitate rapid surface endothelialization. This engineered dual-pathway interference strategy targeting bacterial energy metabolism provides the theoretical guidance for safely reducing the risk of implant infections.