医学
穿孔
生物标志物
内科学
重症监护室
急诊医学
生物化学
化学
冶金
材料科学
冲孔
作者
Kazuhiro Matsuda,Takeshi Aoki,Makoto Watanabe,Katsuhiro Tomioka,Yoshihiko Tashiro,Tomokazu Kusano,Toru Koizumi,Satoru Goto,Kaoru Yamazaki,Koji Otsuka,Masahiko Murakami
标识
DOI:10.1177/00031348211056256
摘要
Colorectal perforation is a serious disease with high mortality requiring emergency surgery. This study aimed to evaluate the role of the endotoxin activity assay (EAA) to assess the severity in patients admitted to the intensive care unit after emergency surgeries for colorectal perforations. Patients were divided into high (EAA ≥.4) and low (EAA <.4) groups based on the EAA levels, and the correlation between the EAA values and clinical variables related to the severity was evaluated. The SOFA scores were significantly higher in the high group than those in the low group. The high EAA value persisted even after 48 hours and extended the ICU length of stay. These results suggest that EAA may be a potential biomarker to assess severity and useful as one of the instrumental in predicting the outcomes for colorectal perforation patients.
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