连翘
牙密螺旋体
医学
口腔卫生
变形链球菌
连翘
唾液
牙龈卟啉单胞菌
核梭杆菌
抗菌剂
消毒剂
牙科
微生物学
内科学
牙周炎
细菌
生物
中医药
金银花
替代医学
病理
遗传学
作者
Ryuta Urakawa,Shibata Takekatsu,Tomomasa Kimura,Nao Gojo,Motofumi Sogou,Takamori Kiyoto,Tsuyoshi Inoue,Kiyoshi Konishi,Takayoshi Sakai
摘要
Aim Matching transformation system (MA-T) is an on-demand aqueous chlorine dioxide solution that realizes excellent safety with various antimicrobial activities even under abundant organic compound. By using MA-T in human oral care, we examined its effectiveness against bacteria causing oral infections such as periodontal disease and dental caries. Materials and Methods The participants of the 75th Annual Meeting of the Japanese Stomatological Society held on May 13 and 14, 2021, were enrolled in this study. Saliva samples were collected on the first day after normal oral care and on the second day after oral care with MA-T. The total number of bacteria and the numbers of Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Streptococcus mutans, and Candida albicans were compared for the two samples on Days 1 and 2. Results Twenty-two subjects met the study criteria. The total bacterial count and the number of T. forsythia on Day 2 were significantly lower than those on Day 1 (p = 0.000177 and p = 0.0186, respectively). The numbers of T. denticola and S. mutans tended to decrease, although not significantly (p = 0.100 and p = 0.251, respectively). Statistical analysis was not performed for P. gingivalis and C. albicans because of sample size. Conclusion MA-T is putatively effective for oral hygiene. MA-T oral care reduces bacteria that cause periodontal disease and dental caries compared with regular oral care. The results of this study suggest that MA-T, a new disinfectant, can be applied to oral care and may reduce periodontal disease, dental caries, and other oral infections.
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