吸附
纤维素
材料科学
复合数
制作
聚合物
化学工程
细菌纤维素
分子印迹聚合物
化学
纳米技术
复合材料
选择性
有机化学
催化作用
医学
替代医学
病理
工程类
作者
Liwei Qian,Yuxuan Yang,Ting Xu,Sufeng Zhang,Valentin Nica,Ruihua Tang,Wei Song
标识
DOI:10.1016/j.carbpol.2022.119835
摘要
The acquisition of efficient protein isolation substances is vital for proteomic research, whereas it's still challenging nowadays. Herein, an elaborately designed protein imprinted material based on a bacterial cellulose@ZIF-67 composite carrier (BC@ZIF-67) is proposed for the first time. In particular, due to the ultrafine fiber diameter and abundant hydroxyl functional groups of the bacterial cellulose, BC@ZIF-67 presented a compact arrangement structure similar to a pearl necklace, which greatly promoted template immobilization and mass transfer resistance in protein imprinting technology. Therefore, the protein-imprinted material (BC@ZIF-67@MIPs) fabricated by surface imprinting technology and template immobilization strategy could exhibit ultrahigh adsorption capacity (1017.0 mg g-1), excellent recognition (IF = 5.98) and rapid adsorption equilibrium time (50 min). In addition, based on the experiment outcomes, our team employed BC@ZIF-67@MIPs to enrich template protein in blended protein solutions and biosamples, identifying them as underlying candidates for isolating and purifying proteins.
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