医学
麻醉
止痛药
安慰剂
随机对照试验
根治性耻骨后前列腺切除术
前列腺切除术
类阿片
外科
前瞻性队列研究
前列腺
内科学
癌症
病理
受体
替代医学
作者
Nabil Elkassabany,Moustafa Ahmed,S. Bruce Malkowicz,Daniel F. Heitjan,Joshua A. Isserman,E. Andrew Ochroch
标识
DOI:10.1016/j.jclinane.2013.04.009
摘要
To compare the efficacy of ultrasound-guided tansversus abdominis plane (TAP) block with placebo for postoperative analgesia after retropubic radical prostatectomy (RRP). Prospective, randomized, double-blinded study. Tertiary-care Veterans Affairs (VA) hospital. ASA physical status 1, 2, and 3 patients scheduled for RRP. Patients were randomized to two groups: the TAP group and the control group. All patients underwent an ultrasound-guided TAP block procedure after induction of general anesthesia and received either local anesthetic (TAP group) or normal saline (control group). Opioid use and verbal analog pain scores at 1, 6, 12, and 24 hours after surgery were recorded, as was the frequency of side effects. Times to ambulation and first oral intake also were recorded. The TAP block group had lower pain scores and required less total opioid in the first 24 hours after surgery. Time to first oral intake and time to ambulation were similar between the two groups. The TAP block has early benefits in postoperative analgesia after RRP.
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