丁酸盐
免疫系统
免疫疗法
癌症研究
甘露糖
卵巢癌
免疫检查点
肿瘤微环境
甘露糖受体
生物
癌症
医学
免疫学
内科学
生物化学
巨噬细胞
发酵
体外
作者
Chen Zhang,Yiying Wang,Mengdi He,Chenyang Wang,Kankan Cao,Yujing Zhong,Xueling Wang,Moran Yang,Guodong Zhang,Jiaqi Lu,Huan Yi,Haiou Liu,Congjian Xu
出处
期刊:Cancer Research
[American Association for Cancer Research]
日期:2025-04-17
卷期号:85 (13): 2468-2484
被引量:9
标识
DOI:10.1158/0008-5472.can-24-3209
摘要
Alterations to the gut microbiome induced by mannose engender an immune stimulatory tumor microenvironment responsive to immunotherapy, suggesting that mannose may be an effective and safe adjuvant therapy for stimulating immunotherapy sensitivity.
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