In April 2024, our hospital confirmed a rare case of intra-abdominal infection by Kodamaea ohmeri. The patient sought medical attention at our hospital after taking painkillers orally for one month, experiencing recurrent abdominal pain for 17 days and worsening for 7 days. In March 2024, the patient received symptomatic treatment with oral analgesics (diclofenac sodium) for arthritis. After 2 weeks of medication, the patient experi-enced upper abdominal colic without any additional triggers. After 3 weeks of medication, the abdominal pain sig-nificantly worsened compared to before, and the pain was persistent. The patient continued to receive oral painkillers for treatment, but there was no significant improvement in symptoms. The patient went to another hospital for treatment with anti-inflammatory infusion (specific details unknown), but the effect was not satisfactory. In order to seek additional treatment, he is now seeking medical attention at our hospital.