Early adverse outcomes remain challenging to prevent in morbidly obese patients undergoing total hip arthroplasty

医学 假体周围 危险系数 混淆 肥胖 体质指数 骨关节炎 关节置换术 内科学 比例危险模型 外科 置信区间 替代医学 病理
作者
Evan M. Dugdale,Mason E. Uvodich,Mark W. Pagnano,Daniel J. Berry,Matthew P. Abdel,Nicholas A. Bedard
出处
期刊:The bone & joint journal [British Editorial Society of Bone & Joint Surgery]
卷期号:106-B (11): 1223-1230 被引量:1
标识
DOI:10.1302/0301-620x.106b11.bjj-2023-1187.r1
摘要

Aims The prevalence of obesity is increasing substantially around the world. Elevated BMI increases the risk of complications following total hip arthroplasty (THA). We sought to evaluate trends in BMI and complication rates of obese patients undergoing primary THA over the last 30 years. Methods Through our institutional total joint registry, we identified 15,455 primary THAs performed for osteoarthritis from 1990 to 2019. Patients were categorized according to the World Health Organization (WHO) obesity classification and groups were trended over time. Cox proportional hazards regression analysis controlling for confounders was used to investigate the association between year of surgery and two-year risk of any reoperation, any revision, dislocation, periprosthetic joint infection (PJI), venous thromboembolism (VTE), and periprosthetic fracture. Regression was stratified by three separate groups: non-obese; WHO Class I and Class II (BMI 30 to 39 kg/m 2 ); and WHO Class III patients (BMI ≥ 40 kg/m 2 ). Results There was a significant increase in the proportion of all obesity classes from 1990 to 2019, and the BMI values within each WHO class significantly increased over time. Risk of any reoperation did not change over time among non-obese or WHO Class I/II patients, but increased for WHO Class III patients (hazard ratio (HR) 1.04; p = 0.044). Risk of dislocation decreased over time for non-obese (HR 0.96; p < 0.001) and WHO Class I/II (HR 0.96; p = 0.002) patients, but did not change over time for WHO Class III (HR 0.94; p = 0.073) patients. Risks of any revision and PJI did not change over time for any group. Conclusion The proportion of patients undergoing THA who are obese has increased dramatically at our institution between 1990 and 2019. Despite BMI values increasing within all WHO classes over time, two-year complication risks have remained stable or decreased in WHO Class I/II patients. However, continued efforts will be required to mitigate risks in the heaviest WHO Class III patients. Cite this article: Bone Joint J 2024;106-B(11):1223–1230.
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