类有机物
转化研究
转化医学
基础研究
再生医学
桥接(联网)
临床实习
个性化医疗
精密医学
构造(python库)
计算机科学
计算生物学
医学
工程伦理学
数据科学
生物信息学
神经科学
生物
干细胞
病理
工程类
细胞生物学
计算机网络
家庭医学
图书馆学
程序设计语言
作者
Guihu Weng,Jinxin Tao,Yueze Liu,Jiangdong Qiu,Dan Su,Ruobing Wang,Wenhao Luo,Taiping Zhang
出处
期刊:Cancer Letters
[Elsevier]
日期:2023-09-01
卷期号:572: 216353-216353
被引量:4
标识
DOI:10.1016/j.canlet.2023.216353
摘要
Nowadays, the diagnosis and treatment system of malignant tumors has increasingly tended to be more precise and personalized while the existing tumor models are still unable to fully meet the needs of clinical practice. Notably, the emerging organoid platform has been proven to have huge potential in the field of basic-translational medicine, which is expected to promote a paradigm shift in personalized medicine. Here, given the unique advantages of organoid platform, we mainly explore the prominent role of organoid models in basic research and clinical practice from perspectives of tumor biology, tumorigenic microbes-host interaction, clinical decision-making, and regenerative strategy. In addition, we also put forward some practical suggestions on how to construct a new generation of organoid platform, which is destined to vigorously promote the reform of basic-translational medicine.
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