倾向得分匹配
吻合
医学
克罗恩病
外科
内窥镜检查
内科学
疾病
作者
Line Alibert,Louis Betton,Alexandre Falcoz,Gilles Manceau,Stéphane Benoist,Philippe Zerbib,Juliette Podevin,Léon Maggiori,Antoine Brouquet,Gaëlle Tyrode,Lucine Vuitton,Déwi Vernerey,Jérémie H. Lefèvre,Zaher Lakkis
出处
期刊:Journal of Crohn's and Colitis
[Oxford University Press]
日期:2023-10-18
被引量:7
标识
DOI:10.1093/ecco-jcc/jjad176
摘要
Postoperative recurrence is a major concern in Crohn's disease. The Kono-S anastomosis has been described to reduce the rate of recurrence. However, the level of evidence for its effectiveness remains low. The KoCoRICCO study aimed to compare outcomes between Kono-S anastomosis and conventional anastomosis in two nationwide prospective cohorts.Adult patients with Crohn's disease who underwent ileocolonic resection with Kono-S anastomosis were prospectively included in seven referral centers between 2020 and 2022. Patients with conventional side-to-side anastomosis were enrolled from a previously published cohort. A propensity score analysis was performed to compare recurrence at first endoscopy in a matched 1:2 ratio population.A total of 433 patients with ileocolonic anastomosis were enrolled, of whom 155 had a Kono-S anastomosis. Before matching, both groups were unbalanced for preoperative, intraoperative, and postoperative characteristics. After matching patients with available endoscopic follow-up, endoscopic recurrence ≥i2 was found in 47.5% of the Kono-S group and 44.3% of the conventional side-to-side group (p=0.6745).The KoCoRICCO study suggests that Kono-S anastomosis does not reduce the risk of endoscopic recurrence in Crohn's disease compared to conventional side-to-side anastomosis. Further research with a longer follow-up is necessary to determine whether there is a potential benefit on surgical recurrence.
科研通智能强力驱动
Strongly Powered by AbleSci AI