Fabrication Water Solubility of Curcumin–Mogroside Self‐Assembly Nanoparticles: Characterization, Antioxidant, and HepG2 Cell Cytotoxicity Activity Evaluation

stacking, hydrophobic interaction, and hydrogen bonding may contribute to the successfully formed self-assembled nanoparticles. Moreover, nanoparticles had significantly enhanced the water solubility of CUR, increasing from 10.7 ng/mL in pure CUR to 1.135 mg/mL in CUR-MOG NPs. The CUR-MOG NPs demonstrated comparable DPPH radical scavenging activity and HepG2 cell cytotoxicity with those of free CUR. CUR-MOG NPs exhibited a superior water-soluble capability, which may serve as a promising system for improving its applications in food and pharmaceutical products.