危险系数
置信区间
优势比
医学
比例危险模型
可能性
人口学
广义估计方程
纵向研究
社会经济地位
老年学
听力损失
内科学
听力学
环境卫生
人口
逻辑回归
统计
社会学
病理
数学
作者
Nicholas S. Reed,Kening Jiang
出处
期刊:Innovation in Aging
[Oxford University Press]
日期:2022-11-01
卷期号:6 (Supplement_1): 292-293
标识
DOI:10.1093/geroni/igac059.1161
摘要
Abstract Hearing Loss (HL) is common among older adults and is associated with factors (e.g., walking speed and social isolation) that may mediate an association with frailty. In the National Health and Aging Trends Study (NHATS) 2011-2018 data, frailty was defined by the physical frailty phenotype composite (exhaustion, low physical activity, weakness, slowness, and shrinking) while HL was self-report. Among, 6897 baseline participants in 2011, 1132 (16%) were frail. In a cox proportional hazard model adjusted for demographic, socioeconomic, and clinical risk factors, HL (n=1607; Hazard Ratio[HR]=1.15; 95% Confidence Interval[CI]=1.00-1.32) was associated with higher risk of incident frailty relative to those with no HL (n=5290). In a generalized estimating equation longitudinal model (2011-2018), HL was associated with higher odds of frailty at baseline (Odds Ratio[OR]=1.52; 95%CI=1.49-1.96) and a 1.06 (95%CI=1.04-1.09) annual increase in odds of frailty. Future research should focus on mechanisms underlying association and determine the impact of HL treatment.
科研通智能强力驱动
Strongly Powered by AbleSci AI