抗菌活性
双金属片
枯草芽孢杆菌
吸光度
银纳米粒子
扫描电子显微镜
核化学
透射电子显微镜
纳米颗粒
材料科学
细菌
化学
纳米技术
金属
生物
色谱法
冶金
复合材料
遗传学
作者
Windri Handayani,Cuk Imawan,Aminah Umar,Yasman Yasman,Retno Yunilawati,Dede Djuhana
出处
期刊:Advances in Natural Sciences: Nanoscience and Nanotechnology
[IOP Publishing]
日期:2021-12-01
卷期号:12 (4): 045007-045007
被引量:1
标识
DOI:10.1088/2043-6262/ac458a
摘要
Abstract The development of new material properties for antimicrobial agents to address the problem of antibiotic resistance is currently being explored. Silver and copper exhibit oligodynamic properties, which inhibit the growth of microorganisms. These properties are stronger at the nanoscale than the macroscale, especially for bimetallic nanoparticles (NPs). In this study, we synthesized bimetallic CuO and Ag NPs using Diospyros discolor Willd. (Velvet apple) leaf extract with three different ratios of Cu and Ag precursors: 1:0.01, 1:0.1, and 1:1 (v/v). In addition, the optical properties of these NPs were characterised using UV-Vis spectrophotometer, which showed the typical absorbance peak in the range of 300–400 nm. The size and shape of the CuO and Ag nanoparticles were analysed using a scanning electron microscope (SEM) and transmission electron microscope (TEM) images. The SEM and TEM images showed leaf-shaped CuO nanoplates and spherical AgNPs. Furthermore, the crystalline properties were analysed using x-ray diffraction (XRD). This study produced CuO-Ag nanoclusters with a particular morphology, size, and composition. The antibacterial assay showed potential broad-spectrum activity for Gram-positive bacteria ( Staphylococcus aureus and Bacillus subtilis ) as well as Gram-negative bacteria ( Escherichia coli and Pseudomonas aeruginosa ).
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