[Effect of antioxidant therapy on indicators of free radical activity in workers at risk of lead exposure].

The authors administered to 36 workers exposed to lead, for four weeks the preparation Prolong which contains vitamin C, vitamin E, beta-carotene, selenium, zinc and chromium and investigated the effect on indicators of free radicals. A statistically significant increase of the following occurred: superoxide dismutase (p < 0.001), glutathione peroxidase (p < 0.01), an increase of the total antioxidant capacity (p < 0.01) and an increase of uricaemia (p < 0.05). Based on these results the authors consider supplementation with antioxidants indicated in workers exposed to lead.