Along with the gradual limit and elimination of polybrominated diphenyl ether(PBDEs) production,the environment pollution status of un-regulated and mass-producing non-PBDEs flame retardants,such as tetrabromobisphenol-A(TBBP-A) has attracted increasing attention and concern.This paper reviews the distribution,bioaccumulation,human exposure and environmental behavior of flame retardant TBBP-A in various environments.