It is very important to research design and implementation of simulation experimental design system,because that it can program problems,prepare simulation scenario,and configure simulation for weapon system-of-systems.Based on inducing the basic principles of the experimental design system of weapon system-of-systems combat simulation,the paper analyzes the requirements of design and experimental design of different system-of-systems simulation experiment modes.It constructs the system's architecture,which contains three modules-problem design,scenario design,and simulation design,and expounds the key technical issues and their solutions.At last,an experiment named Aerial Shield is developed with the prototype of system.