Manganese in Health and Disease

ArticlesManganese in Health and DiseaseGeorge C. CotziasGeorge C. CotziasPublished Online:01 Jul 1958https://doi.org/10.1152/physrev.1958.38.3.503MoreSectionsPDF (5 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Download PDF FiguresReferencesRelatedInformation Cited ByManganese toxicity is targeting an early step in the dopamine signal transduction pathway that controls lateral cilia activity in the bivalve mollusc Crassostrea virginicaComparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, Vol. 213Structural and enzymatic properties of mammalian d-glutamate cyclaseArchives of Biochemistry and Biophysics, Vol. 654Exploring (bio)catalytic activities of structurally characterised Cu( ii ) and Mn( iii ) complexes: histidine recognition and photocatalytic application of Cu( ii ) complex and derived CuO nano-cubes1 January 2018 | Dalton Transactions, Vol. 29Manganese NeurodegenerationMechanistic insight into neurotoxicity induced by developmental insultsBiochemical and Biophysical Research Communications, Vol. 482, No. 3Metallic Burden of Deciduous Teeth and Childhood Behavioral Deficits15 June 2015 | International Journal of Environmental Research and Public Health, Vol. 12, No. 638. Soy-based infant formula associated with increased risk for ADHD8 July 2014Olfactory uptake of manganese requires DMT1 and is enhanced by anemiaThe FASEB Journal, Vol. 21, No. 1Activation Analysis of the Biological Trace Elements31 October 2006Oral manganese for liver imaging at three different field strengths1Academic Radiology, Vol. 11, No. 6Effects of melanin and manganese on dna damage and repair in PC12-derived neuronsFree Radical Biology and Medicine, Vol. 36, No. 9Increased manganese concentration in the liver after oral intake1Academic Radiology, Vol. 11, No. 1Therapeutic and Diagnostic Agents for Parkinson’s Disease15 January 2003Manganese action in brain functionBrain Research Reviews, Vol. 41, No. 1High Dietary Manganese Lowers Heart Magnesium in Pigs Fed a Low-Magnesium DietThe Journal of Nutrition, Vol. 130, No. 8Distribution of injected iron 59 and manganese 54 in hypotransferrinemic miceJournal of Laboratory and Clinical Medicine, Vol. 128, No. 3Manganese and chronic hepatic encephalopathyThe Lancet, Vol. 346, No. 8970Persistent effects of manganese on effortful responding and their relationship to manganese accumulation in the primate globus pallidusToxicology and Applied Pharmacology, Vol. 113, No. 1Role of Trace Elements on Complications in Patients Undergoing Chronic Hemodialysis13 March 2018 | The International Journal of Artificial Organs, Vol. 15, No. 1Abnormalities in hair trace elements as indicators of aberrant behaviorComprehensive Psychiatry, Vol. 32, No. 3The glutathionyl radical formation in the reaction between manganese and glutathione and its neurotoxic implicationsMedical Hypotheses, Vol. 33, No. 2Magnetic resonance imaging studies of the brains of anesthetized rats treated with manganese chlorideBrain Research Bulletin, Vol. 23, No. 3Neurotoxins, parkinsonism and Parkinson's diseasePharmacology & Therapeutics, Vol. 32, No. 1Ingested manganese chloride as a contrast agent for magnetic resonance imagingMagnetic Resonance Imaging, Vol. 5, No. 1Role of Manganese in Chronic Hemodialysis Patients13 March 2018 | The International Journal of Artificial Organs, Vol. 10, No. 1Manganese neurotoxicity: Effects ofl-DOPA and pargyline treatmentsBrain Research, Vol. 367, No. 1-2ECOGENETICS OF PARKINSON'S DISEASE: 4-HYDROXYLATION OF DEBRISOQUINEThe Lancet, Vol. 326, No. 8466The acute toxicity of cyclopentadienyl manganese tricarbonyl in the ratToxicology, Vol. 34, No. 4Divalent transition-metal ions (Cu2+ and Zn2+) in the brains of epileptogenic and normal miceBrain Research, Vol. 280, No. 2Correlations between the concentrations of fluoride and some other constituents in tea infusions and their possible dental caries-preventive effectArchives of Oral Biology, Vol. 28, No. 6The dissulution of a manganese ore in dilute aqueous solutionEnvironment International, Vol. 9, No. 5Determination of manganese in tissues by neutron activation analysis using an antimony pentoxide columnClinica Chimica Acta, Vol. 106, No. 3Effect of stress on the response of rat brain to manganeseToxicology and Applied Pharmacology, Vol. 47, No. 3Early biochemical response of pulmonary tissue to manganese dioxideToxicology, Vol. 8, No. 2Calcium ion effects on guanylate cyclase of brainLife Sciences, Vol. 18, No. 9Effect of manganese on neonatal rat: Manganese distribution in vital organsChemosphere, Vol. 5, No. 5Removal of manganese by chelating agents from brain and liver of manganese treated rats: An in vitro and an in vivo studyToxicology, Vol. 5, No. 2Neutron activation analysis for bulk and trace elements in urineAnalytica Chimica Acta, Vol. 78, No. 2Histochemical alterations in rabbit testis produced by manganese chlorideToxicology and Applied Pharmacology, Vol. 32, No. 3Metals and melanins in the extrapyramidal centersPharmacology & Therapeutics. Part B: General and Systematic Pharmacology, Vol. 1, No. 4Addendum1 January 1975 | Annals of the ICRP/ICRP Publication, Vol. OS_23, No. 1Biochemical Applications of Flame Emission and Atomic Absorption Spectroscopy31 August 2016 | Applied Spectroscopy, Vol. 29, No. 1Parkinsonism and DopaJournal of Chronic Diseases, Vol. 22, No. 5Manganese determination in mammalian bone by neutron activation analysisLife Sciences, Vol. 8, No. 12Essential trace metals in man: ManganeseJournal of Chronic Diseases, Vol. 19, No. 5Trace ElementsThe Lancet, Vol. 287, No. 7446Estimation of manganese in human enamel by activation analysisArchives of Oral Biology, Vol. 11, No. 2The distribution of 54Mn in the enamel and dentine of the rat incisorArchives of Oral Biology, Vol. 10, No. 4Analytical Chemistry of Aqueous Manganese1 January 1965 | Journal - American Water Works Association, Vol. 57, No. 1Chelation of iron by sugarsBiochimica et Biophysica Acta, Vol. 69The Effect of Manganese Chloride on Amelogenesis9 November 2016 | Journal of Dental Research, Vol. 41, No. 1 More from this issue > Volume 38Issue 3July 1958Pages 503-532 https://doi.org/10.1152/physrev.1958.38.3.503PubMed13567045History Published online 1 July 1958 Published in print 1 July 1958 Metrics