冷球蛋白
冷球蛋白
采样(信号处理)
冷球蛋白血症
医学
计算机科学
免疫学
抗体
计算机视觉
滤波器(信号处理)
病毒
丙型肝炎病毒
作者
A. Bakker,J. Slomp,Taede de Vries,Dick A G Boymans,Bert Veldhuis,Kees Halma,Peter Joosten
标识
DOI:10.1515/cclm.2003.015
摘要
Propersample handling is important for the accurate and prompt diagnosis of cryoglobulinaemia as well as for obtaining correct results of other laboratory tests. In this case report, we present two patients for whom improper sampling delayed the diagnosis of cryoglobulinaemia. The routine sampling procedure was not sufficient for detecting these cryoglobulins and we demonstrated that the temperature dropped below 37 degrees C at different steps during the sample preparation. Adjusting the preanalytical procedure revealed that both patients possessed a cryoglobulin with high thermal insolubility. We conclude that in cryoglobulinaemia strict adherence to guidelines to keep the temperature >37 degrees C is crucial for sample collection and must be strongly recommended.
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