A simple method for the quantitative analysis of resin bound thiol groups

Abstract Non-aqueous solutions of Ellman's reagent [5,5′-dithio(2-nitrobenzoic acid), DTNB] can be used to quantify thiols supported on macroporous polystyrene and TentaGel resins. Organic solutions of Ellman's reagent may also be used as a qualitative tests for thiols on a wider range of solid supports.