肠道菌群
肥胖
多糖
胰岛素抵抗
炎症
生物
医学
免疫学
内分泌学
生物化学
作者
Yang Su,Jing Li,Lun Wu,Hai‐Xue Kuang
出处
期刊:PubMed
日期:2021-10-01
卷期号:76 (10): 473-479
被引量:8
摘要
High-calorie food intake and unhealthy lifestyle have considerably raised the incidence of obesity. The gut microbiota is associated with metabolic disorders which promote excessive accumulation of fat, elicit host systemic, low-grade chronic inflammation, and insulin resistance. These features make gut microbiota a promising target for the prevention and intervention of obesity. Herbal polysaccharides in TCM are uneasy to digest by the host, but can be decomposed and utilized by the intestinal flora as the carbon source to mediate bacterial composition. In this review, we are describing the therapeutic effect of polysaccharides on the imbalanced structure of gut microbiota and its metabolites, and discuss the research progress that has been made to unravel the underlying mechanism by which polysaccharides of TCM inhibit the onset and development of obesity.
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