Detection, Contamination, Toxicity, and Prevention Methods of Ochratoxins: An Update Review

赭曲霉毒素 赭曲霉毒素A 真菌毒素 污染 生物技术 食品污染物 毒理 生物 人体净化 食品科学 医学 生态学 病理
作者
Melvin S. Samuel,Kanimozhi Jeyaram,Saptashwa Datta,Narendhar Chandrasekar,Ramachandran Balaji,Selvarajan Ethiraj
出处
期刊:Journal of Agricultural and Food Chemistry [American Chemical Society]
卷期号:69 (46): 13974-13989 被引量:64
标识
DOI:10.1021/acs.jafc.1c05994
摘要

Ochratoxins (OTs) with nephrotoxic, immunosuppressive, teratogenic, and carcinogenic properties are thermostable fungal subordinate metabolites. OTs contamination can occur before or after harvesting, during the processing, packing, distribution, and storage of food. Mold development and mycotoxin contamination can occur in any crop or cereal that has not been stored properly for long periods of time and is subjected to high levels of humidity and temperature. Ochratoxin A (OTA) presents a significant health threat to creatures and individuals. There is also a concern of how human interaction with OTA will also express the remains of OTA from feedstuffs into animal-derived items. Numerous approaches have been studied for the reduction of the OTA content in agronomic products. These methods can be classified into two major classes: inhibition of OTA adulteration and decontamination or detoxification of food. A description of the various mycotoxins, the organism responsible for the development of mycotoxins, and their adverse effects are given. In the current paper, the incidence of OTA in various fodder and food materials is discussed, which is accompanied by a brief overview of the OTA mode of synthesis, physicochemical properties, toxic effects of various types of ochratoxins, and OTA decontamination adaptation methods. To our knowledge, we are the first to report on the structure of many naturally accessible OTAs and OTA metabolism. Finally, this paper seeks to be insightful and draw attention to dangerous OTA, which is too frequently neglected and overlooked in farm duplication from the list of discrepancy studies.
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