选择(遗传算法)
近亲繁殖
遗传多样性
多样性(政治)
基因组选择
杂交
生物
人口
进化生物学
遗传学
计算机科学
人工智能
基因型
人口学
社会学
单核苷酸多态性
基因
人类学
作者
Audrey Ganteil,Torsten Pook,Silvia Teresa Rodríguez‐Ramilo,Bruno Ligonesche,Catherine Larzul
标识
DOI:10.1101/2021.09.22.461330
摘要
Abstract Creating a new synthetic line by crossbreeding means complementary traits from pure breeds can be combined in the new population. Although diversity is generated during the crossbreeding stage, in this study, we analyze diversity management before selection starts. Using genomic and phenotypic data from animals belonging to the first generation (G0) of a new line, different simulations were run to evaluate diversity management during the first generations of a new line and to test the effects of starting selection at two alternative times, G3 and G4. Genetic diversity was characterized by allele frequency, inbreeding coefficients based on genomic and pedigree data, and expected heterozygosity. Breeding values were extracted at each generation to evaluate differences in starting selection at G3 or G4. All simulations were run for ten generations. A scenario with genomic data to manage diversity during the first generations of a new line was compared with a random and a selection scenario. As expected, loss of diversity was higher in the selection scenario, while the scenario with diversity control preserved diversity. We also combined the diversity management strategy with different selection scenarios involving different degrees of diversity control. Our simulation results show that a diversity management strategy combining genomic data with selection starting at G4 and a moderate degree of diversity control generates genetic progress and preserves diversity.
科研通智能强力驱动
Strongly Powered by AbleSci AI