P1727the quality of life after ablative therapy in patients with atrial fibrillation in korea

I. Introduction: We sought to evaluate the influence of ablative therapy on QOL in patients with atrial fibrillation at 6 months after ablation II. Methodology: From January 2010 to August 2013, eighty-seven patients who underwent first catheter ablation for paroxysmal or persistent atrial fibrillation were enrolled in University Medical Center. Both pulmonary veins isolation was done in all patients. Additional linear ablation or electrogram-guided ablation depended on operator’s decision. Before and after ablative therapy at 6 months, patients received a questionnaire for QOL assessment. Heath-related QoL was assessed with the Medical Outcomes Study Short Form-36(SF-36). The SF-36 contains 8 individual scales, scored from 0 (worst health) to 100 (best health). Physical component summary (PCS) and mental component summary (MCS) scores including subscales analysis were assessed. III. Result: After ablative therapy, the physical component summary scores of the Medical Outcomes Study Short Form 36 increased from 67.9±21.6 to 75.1±16.6 (p=0.001). In subscales of physical component, physical functioning increased from 73.6±23.0 to 79.6±18.8 (p=0.006), role-physical increased from 70.2±32.7 to 79.7±30.0 (p=0.008), and body pain increased from 77.2±27.2 to 88.7±19.0 (p<0.001). However, there was no difference in general health before and after ablative therapy (50.8±19.6 vs. 52.2±18.2, p=0.455). After ablative therapy, the mental component summary scores of the Short Form 36 increased from 65.2±19.5 to 69.8±17.0 (p=0.021). In subscales of mental component, only social functioning increased from 80.9± 25.5 to 92.2± 17.8 (p<0.001). There was no difference in role-emotional (74.4±32.4 vs. 77.6±30.6, p=0.331), vitality (48.3±20.6 vs. 47.6±21.3, p=0.751) and mental health (57.2±20.0 vs. 61.5±21.4, p=0.062) IV. Conclusion: Ablative therapy improved the quality of life in patients with AF at 6 months in not only physical component but also mental component.