Effect of Mannoproteins on the Growth, Gastrointestinal Viability, and Adherence to Caco-2 Cells of Lactic Acid Bacteria

Abstract: Yeast cell wall (YCW) preparations and yeast mannoprotein extracts have been effective against some enteropathogenic bacteria as Campylobacter jejuni, Escherichia coli, and Salmonella, and they can affect the population of beneficial lactic acid bacteria (LAB). In this work, we studied the effect of a mannoprotein extract on five strains of LAB. This extract was metabolised by the bacteria, enhancing their survival in simulated gastrointestinal juice, and increasing the adherence of Lactobacillus plantarum, L. salivarius, and Enterococcus faecium to Caco-2 cells. Yeast mannoproteins are promising naturally occurring compounds that could be used to enhance LAB intestinal populations and control pathogens. Practical Application: Mannoproteins could be used to enhance the population of beneficial lactic acid bacteria, improving their growth, gastrointestinal viability and adherence to epithelial intestinal cells.