The Apparent Impunity of the Basal Ganglia to Therapeutic Lesioning: Clinical and Scientific Lessons

Movement Disorders Clinical PracticeVolume 10, Issue S2 p. S42-S46 VIEWPOINT The Apparent Impunity of the Basal Ganglia to Therapeutic Lesioning: Clinical and Scientific Lessons Mariana H.G. Monje MD, PhD, Mariana H.G. Monje MD, PhD orcid.org/0000-0002-0730-4061 HM CINAC (Centro Integral de Neurociencias Abarca Campal), Hospital Universitario HM Puerta del Sur, HM Hospitales, Madrid, Spain Ken and Ruth Davee Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USASearch for more papers by this authorJorge U. Mañez-Miró MD, Jorge U. Mañez-Miró MD orcid.org/0000-0002-8995-8340 HM CINAC (Centro Integral de Neurociencias Abarca Campal), Hospital Universitario HM Puerta del Sur, HM Hospitales, Madrid, Spain PhD Program in Neuroscience, Autónoma de Madrid University-Cajal Institute, Madrid, Spain Neurology Department, IMED Hospitales, Valencia, SpainSearch for more papers by this authorJosé A. Obeso MD, PhD, Corresponding Author José A. Obeso MD, PhD [email protected] HM CINAC (Centro Integral de Neurociencias Abarca Campal), Hospital Universitario HM Puerta del Sur, HM Hospitales, Madrid, Spain Universidad San Pablo-CEU, Madrid, Spain CIBERNED, Instituto de Salud Carlos III, Madrid, Spain Correspondence to: José A. Obeso, CINAC, HM Puerta del Sur University Hospital, Móstoles, Madrid 28939, Spain; E-mail: [email protected]Search for more papers by this author Mariana H.G. Monje MD, PhD, Mariana H.G. Monje MD, PhD orcid.org/0000-0002-0730-4061 HM CINAC (Centro Integral de Neurociencias Abarca Campal), Hospital Universitario HM Puerta del Sur, HM Hospitales, Madrid, Spain Ken and Ruth Davee Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USASearch for more papers by this authorJorge U. Mañez-Miró MD, Jorge U. Mañez-Miró MD orcid.org/0000-0002-8995-8340 HM CINAC (Centro Integral de Neurociencias Abarca Campal), Hospital Universitario HM Puerta del Sur, HM Hospitales, Madrid, Spain PhD Program in Neuroscience, Autónoma de Madrid University-Cajal Institute, Madrid, Spain Neurology Department, IMED Hospitales, Valencia, SpainSearch for more papers by this authorJosé A. Obeso MD, PhD, Corresponding Author José A. Obeso MD, PhD [email protected] HM CINAC (Centro Integral de Neurociencias Abarca Campal), Hospital Universitario HM Puerta del Sur, HM Hospitales, Madrid, Spain Universidad San Pablo-CEU, Madrid, Spain CIBERNED, Instituto de Salud Carlos III, Madrid, Spain Correspondence to: José A. Obeso, CINAC, HM Puerta del Sur University Hospital, Móstoles, Madrid 28939, Spain; E-mail: [email protected]Search for more papers by this author First published: 21 June 2023 https://doi.org/10.1002/mdc3.13787 MDCP Conference on Unmet Needs and Unanswered Questions in Clinical Practice—London, 2021. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1Marsden CD, Obeso JA. The functions of the basal ganglia and the paradox of stereotaxic surgery in Parkinson's disease. Brain 1994; 117(4): 877–897. 10.1093/brain/117.4.877 PubMedWeb of Science®Google Scholar 2Marsden CD. The mysterious motor function of the basal ganglia: the Robert Wartenberg lecture. Neurology 1982; 32(5): 514–539. 10.1212/WNL.32.5.514 CASPubMedWeb of Science®Google Scholar 3Wu T, Hallett M. 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