病理
粘液
气道
免疫系统
免疫学
肺
呼吸上皮
呼吸道
呼吸道疾病
粘液纤毛清除率
哮喘
呼吸系统
小型航空公司
细胞
医学
上皮
炎性细胞
免疫
渗透（HVAC）
作者
Stephen A. Schworer,Hiroaki Murano,Hong Dang,Matthew R. Markovetz,Minako Saito,Takafumi Kato,Takanori Asakura,Gang Chen,Rodney C. Gilmore,L. Morton,Catharina van Heusden,Michael Chua,E.R. Strickler,Zoey Y Wisniewski,Gillian Crisp,Elodie Mitchell,Kayleigh A. Doherty,Shania Mastan,Humberto E. Trejo Bittar,B. Cody
标识
DOI：10.1164/rccm.202409-1849oc
摘要
Asthmatic bronchioles exhibit a T2-driven proximalization associated with mucus plugging. MUC5AC-high niches were identified heterogeneously in bronchiolar epithelia independent of immune cell localizations, suggesting asthmatic bronchioles contain cellular niches which perpetuate T2-initiated epithelial remodeling.
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(2025-6-4)
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