自愈水凝胶
脂质体
药物输送
再生(生物学)
背景(考古学)
癌症治疗
纳米技术
生物相容性材料
癌症治疗
癌症
化学
材料科学
生物医学工程
医学
生物
细胞生物学
内科学
古生物学
有机化学
作者
Mehdi Sanati,Saber Amin Yavari
标识
DOI:10.1016/j.jconrel.2024.03.008
摘要
Drug delivery platforms have gracefully emerged as an indispensable component of novel cancer chemotherapy, bestowing targeted drug distribution, elevating therapeutic effects, and reducing the burden of unwanted side effects. In this context, hybrid delivery systems artfully harnessing the virtues of liposomes and hydrogels bring remarkable benefits, especially for localized cancer therapy, including intensified stability, excellent amenability to hydrophobic and hydrophilic medications, controlled liberation behavior, and appropriate mucoadhesion to mucopenetration shift. Moreover, three-dimensional biocompatible liposome-integrated hydrogel networks have attracted unprecedented interest in tissue regeneration, given their tunable architecture and physicochemical properties, as well as enhanced mechanical support. This review elucidates and presents cutting-edge developments in recruiting liposome-integrated hydrogel systems for cancer treatment and tissue regeneration.
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