T1 rho mapping and native T1 mapping for endogenous assessment of myocardial fibrosis in hypertrophic cardiomyopathy

This study is to examine the feasibility of T1 rho and native T1 mapping for endogenous detection of diffuse and focal myocardial fibrosis in patients with hypertrophic cardiomyopathy (HCM). Results showed that absolute T1 rho increased progressively and significantly from healthy controls to HCM without LGE and then to HCM with LGE, whereas T1 native increased significantly only from healthy controls to HCM with LGE. Besides, both T1 rho and native T1 had moderate correlation with LGE ratio in severe segments.