自愈水凝胶
软机器人
纳米技术
粘附
材料科学
合成生物学
拓扑(电路)
计算机科学
微流控
可控性
组织工程
机器人
人工智能
生物医学工程
工程类
生物信息学
数学
应用数学
高分子化学
电气工程
复合材料
生物
作者
Yang Zhang,Guangyu Bao,Ran Huo,Shuaibing Jiang,Xiaofan Yang,Xiang Ni,Luc Mongeau,Rong Long,Jianyu Li
标识
DOI:10.1073/pnas.2307816120
摘要
Hydrogel adhesion that can be easily modulated in magnitude, space, and time is desirable in many emerging applications ranging from tissue engineering and soft robotics to wearable devices. In synthetic materials, these complex adhesion behaviors are often achieved individually with mechanisms and apparatus that are difficult to integrate. Here, we report a universal strategy to embody multifaceted adhesion programmability in synthetic hydrogels. By designing the surface network topology of a hydrogel, supramolecular linkages that result in contrasting adhesion behaviors are formed on the hydrogel interface. The incorporation of different topological linkages leads to dynamically tunable adhesion with high-resolution spatial programmability without alteration of bulk mechanics and chemistry. Further, the association of linkages enables stable and tunable adhesion kinetics that can be tailored to suit different applications. We rationalize the physics of polymer chain slippage, rupture, and diffusion at play in the emergence of the programmable behaviors. With the understanding, we design and fabricate various soft devices such as smart wound patches, fluidic channels, drug-eluting devices, and reconfigurable soft robotics. Our study presents a simple and robust platform in which adhesion controllability in multiple aspects can be easily integrated into a single design of a hydrogel network.
科研通智能强力驱动
Strongly Powered by AbleSci AI