Preparation and Characterization of Molecular Imprinted Polymers of Tetracycline Antibiotics by Mixed-Templates

Molecular imprinted polymers (MIPs) were synthesized in certain conditions in the experiment when tetracycline antibiotics (TCs), including Oxytetracycline, Chlortetracycline and Tetracycline were used as templates, methacrylic acid as functional monomer, and ethylene glycol dimethacrylate as cross-linker. Oxytetracycline and Chlortetracycline (1:1) were chosen as mixed-templates when the bonding property of the polymer was studied. The results showed that the mixed-templates MIPs had high selection for tetracycline, and were expected to be used as separation materials for the extraction and purification of TCs in animal food.