秀丽隐杆线虫
鞘脂
生物
细胞生物学
信号转导
模式生物
计算生物学
生物化学
基因
作者
Xinzhu Deng,Richard Kolesnick
标识
DOI:10.1515/hsz-2014-0298
摘要
Sphingolipid signaling in Caenorhabditis elegans is vital for sensing environmental change and effecting appropriate cellular response. Many molecular components in sphingolipid intermediary metabolism are conserved throughout evolution. Here we review use of C. elegans as a model system for conducting sphingolipid-based scientific investigation, which has helped us better understand vital roles these remarkable lipids play in human metabolism and disease.
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