双原子分子
催化作用
联轴节(管道)
抗菌活性
过氧化物酶
光热治疗
材料科学
纳米技术
产量(工程)
细菌
化学
组合化学
冶金
分子
生物化学
有机化学
生物
酶
遗传学
作者
Xing Shi,Jie Lv,S. H. M. Deng,Fuxiang Zhou,Jiong Mei,Lei Zheng,Jing Zhang
标识
DOI:10.1002/advs.202305823
摘要
Pathogenic bacteria are the main cause of bacterial infectious diseases, which have posed a grave threat to public health. Single-atom nanozymes have emerged as promising candidates for antibacterial applications, but their activities need to be further improved. Considering diatomic nanozymes exhibit superior metal loading capacities and enhanced catalytic performance, a new interlayer coupling diatomic nanozyme (IC-DAN) is constructed by modulating the coordination environment in an atomic-level engineering. It is well demonstrated that IC-DAN exhibited superior peroxidase-mimetic activity in the presence of H2 O2 to yield abundant ∙OH and possessed high photothermal conversion ability, which synergistically achieves efficient antibacterial therapy. Therefore, IC-DAN shows great potential used as antibacterial agent in clinic and this study open a new route to developing high-performance artificial enzymes.
科研通智能强力驱动
Strongly Powered by AbleSci AI