孟德尔随机化
转录组
药品
计算生物学
免疫系统
生物
药物试验
遗传学
生物信息学
医学
基因
药理学
临床试验
遗传变异
基因表达
基因型
作者
Xueyan Wu,Hui Ying,Qianqian Yang,Qian Yang,Haoyu Liu,Yilan Ding,Huiling Zhao,Zhihe Chen,Ruizhi Zheng,Hong Lin,Shuangyuan Wang,Mian Li,Tiange Wang,Zhiyun Zhao,Min Xu,Yuhong Chen,Yu Xu,Emma E. Vincent,Maria Carolina Borges,Tom R. Gaunt
标识
DOI：10.1038/s41467-024-53621-7
摘要
Immunity has shown potentials in informing drug development for cardiometabolic diseases, such as type 2 diabetes (T2D) and coronary artery disease (CAD). Here, we performed a transcriptome-wide Mendelian randomization (MR) study to estimate the putative causal effects of 11,021 gene expression profiles during CD4
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(2025-6-4)
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