A novel sensor based on Ti3C2 MXene/Co3O4/carbon nanofibers composite for the sensitive detection of 4-aminophenol

A novel, sensitive Ti3C2 MXene/Co3O4/carbon nanofibers (Ti3C2 MXene/Co3O4/CNFs) composite was synthesized via a HF exfoliating Ti3AlC2 strategy, followed by doping Co3O4 and Ti3C2 MXene into the CNFs via a combination electrospinning and thermal annealing process. Ti3C2 MXene/Co3O4/CNFs composite exhibits higher catalytic effect, conductivity, chemical stability, and electrochemical performance than Co3O4 and Ti3C2 MXene in electrochemical impedance, differential pulse stripping voltammetry, chronocoulometry, and cyclic voltammetry tests. This Ti3C2 MXene/Co3O4/CNFs hybrid modified electrode provides fast analysis of 4-aminophenol (4-AP) with ultrahigh sensitivity, enhanced reproducibility and strong anti-interference capability. Furthermore, the level of 4-AP was quantified by this electrode with a wide linear range from 0.5 to 150 μM (R2 > 0.99) and a low detection limit about 0.018 μM was achieved. Finally, the fabricated electrode was used for fast and sensitive analysis of 4-AP spiked in tap water and blood serum samples. This work presents the new Ti3C2 MXene/Co3O4/CNFs electrode provides a platform for 4-AP monitoring and has the advantages of high selectivity, accuracy, simplicity, and rapid analysis.