Integrated application of selenium and silica reduce arsenic accumulation and enhance the level of metabolites in rice grains

In this study, rice plants were co-exposed to selenium (Se) and silica (Si) under arsenic (As) stress to evaluate As accumulation in rice grains, associated cancer risk, and its impact on the types and numbers of grain metabolites. A total of 58 metabolites were identified, of which, 19 belong to sugars, and drastically altered during different treatments. Arsenic exposure significantly reduced monosaccharides,