生物膜
材料科学
搪瓷漆
活性氧
刷子
自愈水凝胶
涂层
纳米技术
复合材料
化学
细菌
高分子化学
遗传学
生物
生物化学
作者
Qun Li,Jinbiao Liu,Yingying Xu,Huijie Liu,Jiao Zhang,Yanan Wang,Yue Sun,Mengzhen Zhao,Lei Lan,Xiaolei Wang
标识
DOI:10.1021/acsami.2c00887
摘要
Biofilm-driven caries and tooth discoloration are two major problems in oral health care. The current methods have the disadvantages of insufficient biofilm targeting and irreversible enamel damage. Herein, an injectable sodium alginate hydrogel membrane doped with bismuth oxychloride (Bi12O17Cl2) and cubic cuprous oxide (Cu2O) nanoparticles was designed to simultaneously achieve local tooth whitening and biofilm removal through a photodynamic dental therapy process. This fast cross-linked hydrogel could form a biofilm removal coating on the target tooth surface precisely. Afterward, reactive oxygen species was effectively released on demand under green light, which could not only eradicate the biofilm but also whiten the tooth non-destructively in a facile manner without significant damage to both the enamel and biological cells. After the usage, the removal of this hydrogel can also enhance the effect of biofilm destruction and caries prevention.
科研通智能强力驱动
Strongly Powered by AbleSci AI