An improved synthetic approach to thieno[2,3‐d]‐1,2,3‐thiadiazolecarboxylates via diazotization of aminothiophene derivatives

Abstract The common synthetic method for the synthesis of fused 1,2,3‐thiadiazoles via diazotization is not generally applicable to aminothiophenes. A substantially improved experimental protocol for the preparation of the title compounds as a potential inducer of systemic acquired resistance in plants is reported based on a novel cyclization mechanism via a Huisgen‐White type rearrangement.