Study on Lignans from the Branch of Daphne genkwa

Objective: To study lignans from the branch of Daphne genkwa Sieb. et Zucc. Methods: The compounds were isolated and repeatedly purified by silica gel,TLC,Sephadex LH-20,and RP-C18 column chromatographic methods,and their structures were elucidated on the basis of physic-chemical constants and spectral analysis. Results: Eight compounds were obtained and elucidated as sesamin(1),syringaresinol( 2),lariciresinol( 3),(-)-pinoresinol( 4),wikstromol( 5),salicifoliol(6),vladinol D(7),isolariciresinol(8). Conclusion: Compound 8 was isolated from the branch of Daphne genkwa for the first time. Compounds 1,5,6 and 7 were separated from the Thymelaeaceae for the first time.