医学
灾难性抗磷脂综合征
心源性休克
狼疮抗凝剂
心脏病学
抗磷脂综合征
抗核抗体
射血分数
休克(循环)
血栓形成
内科学
心力衰竭
心肌病
抗体
心肌梗塞
免疫学
自身抗体
作者
Bożena Zięba,Agnieszka Węgrzyn,Andrzej Mital,Maria Szczepińska-Nowak,Łukasz Lewicki,Michał Chmielecki,Wiesław Puchalski,Andrzej Rynkiewicz
出处
期刊:PubMed
日期:2009-07-01
卷期号:67 (7): 769-73
被引量:1
摘要
A case of a 29-year-old woman 18 days after delivery with catastrophic antiphospholipid syndrome secondary (CAPS) due to undiagnosed systemic lupus erythematosus, leading to cardiogenic shock is reported. Laboratory evaluation revealed increased anticardiolipin antibodies, lupus anticoagulant, antinuclear antibody and thrombocytopenia. Left ventricular ejection fraction was 20%, neurologic deficit and acute renal failure were also present. Cardiac involvement is common in CAPS, but cardiomyopathy due to microvascular thrombosis is rare. CAPS should be considered as a cause of acute heart failure in a women with systemic lupus erythematosus. In the presented case early therapy with anticoagulants, steroids, immunoglobulins and plasmaferesis was beneficial.
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