生物
甲基化
DNA甲基化
基因
表观遗传学
基因表达
男科
分子生物学
遗传学
医学
作者
LI Qi-xian,Kaicheng Zhou,Demin Du,Yali Chen,Dekang Liu,Xiaowei Guan
标识
DOI:10.1016/j.gep.2021.119199
摘要
The family with sequence similarity 83 member (FAM83D) plays important role in the process of cell division as well as tumour progression. However, the role of FAM83D in tissue development was not well explored. Here, we assessed transcriptional levels of FAM83D and other possibly related genes in organs of mice at different ages and methylation level of FAM83D promoter. Our results indicate the trend of FAM83D expression in mouse testis, liver, lung and small intestine, and its relationship to CYCLINB1 and KI67. Finally, we found no effect of promoter methylation status on FAM83D expression during mice development.
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