Aims: Flowering time is critical for plant reproductive success.Plant species, especially which are widely distributed, are observed to exhibit significant differentiation in flowering time to maximize their fitness.In order to explore the molecular mechanism of adaptive differentiation of flowering time in plants, it is essential to clarify the regulating pathways of flowering.This paper summarizes the genetic pathways that regulate flowering time in various groups of plants, which can provide important reference for molecular mechanism research of adaptive differentiation of flowering time.Progresses: As a vital transition from vegetative growth to reproduction in plants, the flowering time has been reported to be regulated by both extrinsic and intrinsic factors.Based on researches of the model plant Arabidopsis thaliana and other taxa, six pathways that regulate flowering time have been identified.The light-dependent pathway, vernalization pathway, and temperature pathway refer to the regulation of flowering time in response to day length or quality of light, a long period of cold exposure, and external high or low temperature, respectively.While the gibberellin pathway, the •综述•