Triazolopyrimidines identified as reversible myeloperoxidase inhibitors
作者
Franck J. Duclos,Lynn M. Abell,David Harden,Kristen Pike,Kimberly Nowak,Gregory A. Locke,Gerald J. Duke,Xiaoqin Liu,Gayani Fernando,Scott A. Shaw,Benjamin Vokits,Nicholas R. Wurtz,Andrew Q. Viet,Meriah N. Valente,Sylwia Stachura,Paul G. Sleph,Javed Khan,Ji Gao,Ashok R. Dongré,Lei Zhao
出处
期刊：MedChemComm [Royal Society of Chemistry] 日期：2017-01-01卷期号：8 (11): 2093-2099被引量：29
A novel myeloperoxidase inhibitor, 7-benzylether triazolopyrimidine was discovered which reversibly inhibits enzyme activity and shows pharmacodynamic effects in mouse models.
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(2025-6-4)
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