慢性阻塞性肺病
肺
医学
细胞毒性
启动(农业)
免疫学
细胞毒性T细胞
体外
生物
内科学
生物化学
植物
发芽
作者
Donna K. Finch,Valerie R. Stolberg,John Ferguson,Henrih Alikaj,M.R. Kady,Bradley W. Richmond,Vasiliy V. Polosukhin,Timothy S. Blackwell,Lisa McCloskey,Jeffrey L. Curtis,Christine M. Freeman
标识
DOI:10.1164/rccm.201712-2513oc
摘要
Heightened NK cytotoxicity against lung epithelial cells in COPD results primarily from lung DC-mediated priming via IL-15 trans-presentation on IL-15Rα. Future studies are required to test whether increased NK cytotoxicity contributes to COPD pathogenesis.
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