EP01.02: Prenatal evaluation, imaging features and neurodevelopmental outcome of prenatally diagnosed periventricular pseudocysts

To determine whether findings in addition to periventricular pseudocysts (PVPC) affect the outcome, characterise PVPC related factors, and describe the differences between connatal cysts and subependymal pseudocysts (SEPC). A retrospective study of PVPC detected prenatally on fetal MRI in 26 fetuses. The fetuses were divided into group A (n = 8), which included cases with isolated PVPC, and Group B (n = 18), which included cases of PVPC with additional findings. Cases were further subdivided into connatal cysts and SEPC. Data collected included: prenatal history, MRI features, sonographic follow up, and neurodevelopmental outcome. To determine whether findings in addition to periventricular pseudocysts (PVPC) affect the outcome, characterise PVPC related factors, and describe the differences between connatal cysts and subependymal pseudocysts (SEPC). All cases in group A (n = 8) had a normal outcome. In group B (n = 18) six pregnancies were terminated and two had an abnormal outcome. 80% of the cases in the connatal cysts subgroup and 55% in the SEPC subgroup had a normal outcome. No significant association was found between the morphological features on MRI and the neurodevelopmental outcome. Neurodevelopmental outcome in isolated PVPC detected prenatally appear to be normal. Additional findings on MRI, including mild to moderate dilated ventricles, asymmetrical ventricles, or T2 hyperintense signal in the white matter without other findings or major fetal abnormality, appear to be benign. Connatal cysts appear to be benign.