雅罗维亚
赤藓糖醇
甘油
肺表面活性物质
多元醇
化学
食品科学
甘露醇
生物化学
色谱法
酵母
有机化学
聚氨酯
作者
Magdalena Rakicka,Anita Rywińska,Krzysztof Cybulski,Waldemar Rymowicz
标识
DOI:10.1016/j.bjm.2016.01.011
摘要
Various chemical compounds, including surfactants, when introduced to culture media may increase the permeability of cellular membranes and thereby affect the quantity of metabolites excreted by cells. The aim of the present study was to evaluate the impact of detergents including Triton X-100, Span 20 and Tween 80 on erythritol production from glycerol by Yarrowia lipolytica Wratislavia K1 in a shake-flask experiment, batch and fed-batch cultures. When Span 20 was added to a fed-batch culture with glycerol as a carbon source (300gL(-1)), erythritol production increased by 15% compared to the culture without the surfactant where it reached 142gL(-1) after 5 days, which corresponded to 0.47gg(-1) yield and productivity of 1.1gL(-1)h(-1). Therefore, it was concluded that Span 20 considerably enhanced the production of this polyol from glycerol.
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