The contrast observation of mosapride and domperidone on treating functional dyspepsia

Objective To compare the clinical curative effect between Mosapride and Domperidone and estimate their curative effect and safety.Methods 173 Patients with FD were divided into 2 groups randomly.The treatment group was given Mosapride 5 mg one tablests,three times a days half-hour before the meal;The controlled group was given Domperidone 10 mg one tablests three times a day.half-hour before the meal.Results There was no significant difference between the two groups on symptomatic relief in one week and two weeks.However,there was obvious difference between two weeks' treatment and one week's treatment for both of their symptomatic relief.Conclusion Mosapride and Domperidone can relieve the symptoms of FD.The two-week-treatment disappearance rates of symptoms are higher than that of one week's treatment.There is no significant difference between two weeks' treatment and one week's treatment for both of their symptomatic relief.So two weeks' treatment of FD with Mosapride and Domperidone can be recommended.