自身免疫性溶血性贫血
溶血
医学
溶血性贫血
免疫学
贫血
抗体
红细胞
红细胞
地中海贫血
作者
Surbhi Shah,Leslie Padrnos
标识
DOI:10.1016/j.hoc.2021.12.003
摘要
Autoimmune hemolytic anemia (AHIA) is the group of acquired autoimmune conditions resulting from the development of autologous antibodies directed against autologous red blood cell antigens resulting in red cell lysis. Beyond the presence, severity, and duration of hemolysis which can lead to symptomatic anemia, additional complications at presentation and during treatment require a high degree of clinical vigilance. These include among others cutaneous, thrombotic, renal disorders, and infectious disorders. Complications can be due to the presence of the pathologic antibody itself, the process of hemolysis, or attributed to treatment. Comprehensive management of AIHA requires awareness and assessment of complications at diagnosis, during, and following treatment.
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